Phenacyl bromide → HCID 178444626, 화합물
반응식
C#CCCCCC=O.c1ccc(C(=O)CBr)cc1>C[Si](C)(C)OC(c1ccccc1)(c1ccccc1)[C@@H]1CCCN1.[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].Cl[Ru]Cl.c1ccc(nc1)-c2ccccn2.c3ccc(nc3)-c4ccccn4.c5ccc(nc5)-c6ccccn6.CN(C)C=O.Cc1cccc(C)n1>C#CCCC[C@@H](C=O)CC(=O)c1ccccc1.C#CCCC[C@H](C=O)CC(=O)c1ccccc1참가 물질
8
반응물 3
생성물 2
시약·촉매·용매 3
반응 조건
- 온도
- 22 °C
후처리
- aliquot4 uL mixture of each reacted solution was collected and diluted with 36 uL ACN
- addition4 uL mixture of each reacted solution was collected and diluted with 36 uL ACN
- additionchiral resolving regent (150 mM in DCM, 40 uL)
- additionCuI with DIPEA (400 mM in ACN) 40 uL
- additioninternal standard 1-phenylprop-2-yn-1-ol (4) (25 mM in ACN) 40 uL
- stirring기록된 절차가 없습니다
- aliquotAfter the reaction, 10 uL of supernatant for each reaction was transferred to another 96-well plate
- additionAfter the reaction, 10 uL of supernatant for each reaction was transferred to another 96-well plate and diluted with 190 uL ACN before the IM-MS analysis
출처 및 근거
- ORD 기록
- ord-ab72a1b17c2a4b34a7f3ec52b3f02495
- 출처 데이터셋
- Dataset from `Ultra-high-throughput mapping of the chemical space of asymmetric catalysis enables accelerated reaction discovery`
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