2-Nitrobenzamide → HCID 22493374, 화합물

반응식

[N+:1]([C:4]1[CH:12]=[CH:11][CH:10]=[CH:9][C:5]=1[C:6]([NH2:8])=[O:7])([O-:3])=[O:2].CO[CH:15](OC)[N:16]([CH3:18])[CH3:17]>>[CH3:15][N:16]([CH:18]=[N:8][C:6](=[O:7])[C:5]1[CH:9]=[CH:10][CH:11]=[CH:12][C:4]=1[N+:1]([O-:3])=[O:2])[CH3:17]

참가 물질

반응물 2

HCID 118762-Nitrobenzamide

HCID 78373Dimethylformamide dimethyl acetal

생성물 1

HCID 22493374HCID 22493374, 화합물

반응 조건

온도: 100 °C

실험 절차

2-Nitrobenzamide (2.5 g, 15 mmol) was dissolved in dimethylformamide-dimethylacetal (10 mL) and heated to 100° C. for 1 hour. Upon cooling, the reaction mixture was placed in a freezer at −23° C. overnight. The white precipitate was collected by filtration and rinsed with hexane to provide N-[(dimethylamino)methylene]-2-nitrobenzamide (3.06 g), which was used without further purification.

후처리

temperatureUpon cooling
filtrationThe white precipitate was collected by filtration
washrinsed with hexane

출처 및 근거

ORD 기록: ord-0fe6797b1e69448d93a56ecc78c61001
출처 데이터셋: uspto-grants-2005_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06884801B1

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