2-Chloro-7,7-dimethyl-7,8-dihydroquinolin-5(6H)-one → 2-Isobutoxy-7,7-dimethyl-7,8-dihydro-6H-quinolin-5-one hydrochloride

HRID 1817818노트

반응식

HRID 1817818 반응식
[Cl:1][C:2]1[CH:11]=[CH:10][C:9]2[C:8](=[O:12])[CH2:7][C:6]([CH3:14])([CH3:13])[CH2:5][C:4]=2[N:3]=1>C(O)C(C)C>[ClH:1].[CH2:8]([O:12][C:2]1[CH:11]=[CH:10][C:9]2[C:8](=[O:12])[CH2:7][C:6]([CH3:14])([CH3:13])[CH2:5][C:4]=2[N:3]=1)[CH:9]([CH3:10])[CH3:4]

참가 물질

3

반응물 1

HCID 148125452-Chloro-7,7-dimethyl-7,8-dihydroquinolin-5(6H)-one

생성물 1

HCID 690385882-Isobutoxy-7,7-dimethyl-7,8-dihydro-6H-quinolin-5-one hydrochloride수율 35%

시약·촉매·용매 1

HCID 6560Isobutanol용매

실험 절차

In analogy to the procedure described in Example 9, 2-chloro-7,7-dimethyl-7,8-dihydro-6H-quinolin-5-one was treated with iso-butyl alcohol to give the title compound in 35% yield.

출처 및 근거

ORD 기록
ord-31f381eb02a646eaaefb6d89be1b36f9
출처 데이터셋
uspto-grants-2009_10
특허 번호
US07598384B2

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