Acetic Anhydride → Ethyl (acetyloxy)(4-chloro-3-nitrophenyl)acetate

HRID 1818690노트

반응식

HRID 1818690 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([OH:14])[C:9]([O:11][CH2:12][CH3:13])=[O:10])=[CH:4][C:3]=1[N+:15]([O-:17])=[O:16].[C:18](OC(=O)C)(=[O:20])[CH3:19]>N1C=CC=CC=1>[C:18]([O:14][CH:8]([C:5]1[CH:6]=[CH:7][C:2]([Cl:1])=[C:3]([N+:15]([O-:17])=[O:16])[CH:4]=1)[C:9]([O:11][CH2:12][CH3:13])=[O:10])(=[O:20])[CH3:19]

참가 물질

4

반응물 2

HCID 7918Acetic AnhydrideHCID 86609828Ethyl (4-chloro-3-nitrophenyl)(hydroxy)acetate

생성물 1

HCID 86609827Ethyl (acetyloxy)(4-chloro-3-nitrophenyl)acetate

시약·촉매·용매 1

HCID 1049Pyridine용매

실험 절차

To a solution (6 mL) of the compound (1.46 g) prepared in Example 22 in pyridine, acetic anhydride (2 mL) was added, and the mixture was stirred for 1 hour at room temperature. The title compound (135 mg) having the following physical data was obtained by concentrating the reaction mixture and azeotroping in toluene.

출처 및 근거

ORD 기록
ord-9e2365e5b0af43d5862d6e13decfd23a
출처 데이터셋
uspto-grants-2009_10
특허 번호
US07601712B2

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