4-Nitrobenzaldehyde → HCID 178477495, 화합물

HRID 1822482노트

반응식

HRID 1822482 반응식
O=Cc1ccc([N+](=O)[O-])cc1.CCSC(=O)C(OCc1ccccc1)C(=O)O>NCc1ccccc1.O=C(O)C(F)(F)F.CN(C)c1ccncc1.CN(C)C=O>CCSC(=O)/C(=C/c1ccc([N+](=O)[O-])cc1)OCc1ccccc1

참가 물질

6

반응물 2

HCID 5414-NitrobenzaldehydeHCID 178477513HCID 178477513, 화합물

생성물 1

HCID 178477495HCID 178477495, 화합물수율 71%

시약·촉매·용매 3

HCID 142844-(Dimethylamino)pyridine시약HCID 12484433Benzenemethanamine, trifluoroacetate촉매HCID 6228Dimethylformamide용매

반응 조건

온도
25 °C

후처리

  1. temperatureThe product mixture was cooled to 25 °C.
  2. filtrationFiltered through a pad of celite · Organic 상 유지
  3. wash"The celite was washed with ethyl acetate (3 x 1 mL)."
  4. concentrationThe filtrate was concentrated under reduced pressure
  5. additionA 0.07 M stock solution of the internal standard ethylene carbonate (0.70 mL in CDCl3) was added.

출처 및 근거

ORD 기록
ord-cea0e0e42a174a3fa38538e7667e472a
출처 데이터셋
Bayesian optimization of 5 decarboxylative olefination reactions

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