Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phosphorus oxychloride → 2-(4-Chlorophenyl)4-chloro-5,6,7,8-tetrahydroquinazoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phosphorus oxychloride | HCID 24813 | — |
| 반응물 | HCID 178517489 | HCID 178517489 | — |
| 생성물 | 2-(4-Chlorophenyl)4-chloro-5,6,7,8-tetrahydroquinazoline | HCID 11196721 | — |
반응 단계
8.0 g of 2-(4-chlorophenyl)-4-hydroxy-5,6,7,8-tetrahydroquinazoline were heated to 100° C. in 10 ml of phosphorus oxychloride. After 3 hours, the cooled solution was carefully poured onto ice water. The crystalline product was filtered off with suction, washed well with water and dried in vacuo at room temperature. Yield: 6.2 g; m.p.: 121° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07045526B2 |
| 출처 데이터셋 | uspto-grants-2006_05 |
| ORD ID | ord-17378f48516545b6a8122404210c0143 |
| 출처 메모 | uspto-grants-2006_05 |