Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(5-Trifluoromethyl-pyridin-2-yloxy)-phenol → 4-Benzyl-piperidine-1-carboxylic acid 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenyl Ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(5-Trifluoromethyl-pyridin-2-yloxy)-phenol | HCID 155241 | — |
| 반응물 | 1-methyl-3-(4-benzyl-piperidine-1-carbonyl)-3H-imidazol-1-ium iodide | HCID 86589190 | — |
| 생성물 | 4-Benzyl-piperidine-1-carboxylic acid 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenyl Ester | HCID 23635636 | — |
반응 단계
The title compound was prepared from 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenol and 1-methyl-3-(4-benzyl-piperidine-1-carbonyl)-3H-imidazol-1-ium iodide. The crude product was purified by flash chromatography using a Quad flash 25 (ethyl acetate/heptane (1:6), (72%, white crystals). HPLC-MS m/z=457.2 (M+1), Rt: 6.0 min.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07067517B2 |
| 출처 데이터셋 | uspto-grants-2006_06 |
| ORD ID | ord-ab67c03345434f0c9e963b367cff9ad4 |
| 출처 메모 | uspto-grants-2006_06 |