4-Morpholinecarbonyl chloride → HCID 23635767, 화합물

HRID 1831153노트

반응식

HRID 1831153 반응식
[Cl:1][C:2]1[C:3]([O:9][C:10]2[CH:15]=[CH:14][C:13]([OH:16])=[CH:12][CH:11]=2)=[N:4][CH:5]=[C:6]([Cl:8])[CH:7]=1.[N:17]1([C:23](Cl)=[O:24])[CH2:22][CH2:21][O:20][CH2:19][CH2:18]1>>[Cl:1][C:2]1[C:3]([O:9][C:10]2[CH:15]=[CH:14][C:13]([O:16][C:23]([N:17]3[CH2:22][CH2:21][O:20][CH2:19][CH2:18]3)=[O:24])=[CH:12][CH:11]=2)=[N:4][CH:5]=[C:6]([Cl:8])[CH:7]=1

참가 물질

3

반응물 2

HCID 848104-Morpholinecarbonyl chlorideHCID 6208804-(3,5-Dichloro-pyridin-2-yloxy)-phenol

생성물 1

HCID 23635767HCID 23635767, 화합물

실험 절차

The title compound was prepared from 4-(3,5-dichloro-pyridin-2-yloxy)-phenol and morpholine-4-carbonyl chloride. The crude product was purified by preparative HPLC (45%, crystals. HPLC-MS m/z=369.1 (M+1), Rt: 4.3 min.

후처리

  1. customThe crude product was purified by preparative HPLC (45%, crystals

출처 및 근거

ORD 기록
ord-f12df9f8119b41658b768d3a2fecfa5e
출처 데이터셋
uspto-grants-2006_06
특허 번호
US07067517B2

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