Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Lithium hydroxide, monohydrate → 3-[2-(2,4-Dichloro-phenyl)-acetylamino]-4-methoxy-benzoic Acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Lithium hydroxide, monohydrate | HCID 168937 | — |
| 반응물 | 3-[2-(2,4-Dichloro-phenyl)-acetylamino]-4-methoxy-benzoic acid methyl ester | HCID 69652265 | — |
| 용매 | Hydrochloric Acid | HCID 313 | — |
| 용매 | Methanol--water (1/1) | HCID 22242641 | — |
| 생성물 | 3-[2-(2,4-Dichloro-phenyl)-acetylamino]-4-methoxy-benzoic Acid | HCID 22052488 | — |
반응 단계
To a solution of 400 mg 3-[2-(2,4-Dichloro-phenyl)-acetylamino]-4-methoxy-benzoic acid methyl ester in 5 ml MeOH/H2O 2:1 56 mg lithium hydroxide monohydrate were added and the mixture was stirred over night. The suspension was diluted with 5 ml concentrated HCl to precipitate the acid. After filtration the filter cake was washed twice with water and then dried to yield the acid as a white powder.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07067665B2 |
| 출처 데이터셋 | uspto-grants-2006_06 |
| ORD ID | ord-69c7a0c252af43e5b0a9aa16263b32a2 |
| 출처 메모 | uspto-grants-2006_06 |