HCID 54724162, 화합물 → HCID 22050728, 화합물

HRID 1831904노트

반응식

HRID 1831904 반응식
[F:1][C:2]1[CH:3]=[C:4]([CH:14]=[CH:15][CH:16]=1)[CH2:5][N:6]1[CH:11]=[CH:10][C:9](O)=[CH:8][C:7]1=[O:13]>C(N)C1C=CC=CC=1>[CH2:5]([NH:6][C:9]1[CH:10]=[CH:11][N:6]([CH2:5][C:4]2[CH:14]=[CH:15][CH:16]=[C:2]([F:1])[CH:3]=2)[C:7](=[O:13])[CH:8]=1)[C:4]1[CH:14]=[CH:15][CH:16]=[CH:2][CH:3]=1

참가 물질

3

반응물 1

HCID 54724162HCID 54724162, 화합물

생성물 1

HCID 22050728HCID 22050728, 화합물

시약·촉매·용매 1

HCID 7504Benzylamine용매

실험 절차

Heated a reaction mixture of 1-(3-fluorobenzyl)-4-hydroxypyridin-2(1H)-one (1.005 g, 4.5 mmol) in benzylamine (15 mL) at reflux (1850 C) under nitrogen atmosphere for 24 h. The reaction was monitored by ES-MS (MH+ 309). The solvent was removed by vacuum distillation to give a yellow residue.

후처리

  1. temperatureHeated
  2. temperatureat reflux (1850 C) under nitrogen atmosphere for 24 h
  3. customThe solvent was removed by vacuum distillation
  4. customto give a yellow residue

출처 및 근거

ORD 기록
ord-f1ef2509faa946738ccd34054eb5e675
출처 데이터셋
uspto-grants-2006_06
특허 번호
US07067540B2

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