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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1832793생성일: 2026년 10월 26일

3-Chloro-4-(propane-2-sulfonyl)-thiophene-2-carbonyl chloride → 3-Chloro-N-(6-{4-[3-(isobutyrylamino)phenyl]-1-piperidinyl}hexyl)-4-(isopropylsulfonyl)-2-thiophenecarboxamide

https://huagongshe.com/reaction/1832793

반응식

참여 물질

역할이름HCID투입량
반응물3-Chloro-4-(propane-2-sulfonyl)-thiophene-2-carbonyl chlorideHCID 2778695—
반응물N-{3-[1-(6-Aminohexyl)4-piperidinyl]phenyl}-2-methylpropanamideHCID 16755868—
용매TetrahydrofuranHCID 8028—
생성물3-Chloro-N-(6-{4-[3-(isobutyrylamino)phenyl]-1-piperidinyl}hexyl)-4-(isopropylsulfonyl)-2-thiophenecarboxamideHCID 22049587—

반응 단계

Prepared by Procedure Q1 (THF) and Scheme AT using N-{3-[1-(6-aminohexyl)-4-piperidinyl]phenyl}-2-methylpropanamide and 3-chloro-4-(isopropylsulfonyl)-2-thiophenecarbonyl chloride: ESMS m/e: 596.2 (M+H)+.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07067534B1
출처 데이터셋uspto-grants-2006_06
ORD IDord-367e2847d11348c8b9807c949ffac115
출처 메모uspto-grants-2006_06