Indole → 1-(3-Chloropropyl)-1H-indole

HRID 1832975노트

반응식

HRID 1832975 반응식
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=[CH:2]1.Br[CH2:11][CH2:12][CH2:13][Cl:14]>>[Cl:14][CH2:13][CH2:12][CH2:11][N:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=[CH:2]1

참가 물질

3

반응물 2

HCID 798IndoleHCID 80061-Bromo-3-chloropropane

생성물 1

HCID 220489601-(3-Chloropropyl)-1H-indole

실험 절차

Prepared by Procedure AH, and Scheme P using 1H-indole and 1-bromo-3-chloropropane: 1H NMR (400 MHz, CDCl3) δ 7.70–7.04 (m, 5H), 6.50 (d, 1H, J=2.8 Hz), 4.31 (t, 2H, J=6.8 Hz), 3.42 (t, 2H, J=6.4 Hz), 2.28–2.20 (m, 2H).

후처리

  1. customPrepared by Procedure AH, and Scheme P

출처 및 근거

ORD 기록
ord-b676600caf5f40e7805ac8c8dde46dfd
출처 데이터셋
uspto-grants-2006_06
특허 번호
US07067534B1

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