HCID 12736922, 화합물 → HCID 12736925, 화합물

반응식

[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[O:14][C:13]3[C:12](=[O:15])[C:11]([C:16]([O:18]CC)=[O:17])=[CH:10][NH:9][C:8]=3[C:7](=[O:21])[C:6]=2[CH:22]=1>Cl>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[O:14][C:13]3[C:12](=[O:15])[C:11]([C:16]([OH:18])=[O:17])=[CH:10][NH:9][C:8]=3[C:7](=[O:21])[C:6]=2[CH:22]=1

참가 물질

실험 절차

A suspension of ethyl 8-chloro-4,10-dihydro-4,10-dioxo-1H-1-benzopyrano[3,2-b]pyridine-3-carboxylate (3.0 g, 0.0094 mole) in 6N hydrochloric acid (100 ml ) was refluxed under nitrogen for 15 hrs., cooled and filtered. The residue was washed with water and with acetone. Recrystallization from DMF gave white crystals (2.4 g, 87%), m.p. 325°-327°.

후처리

temperaturewas refluxed under nitrogen for 15 hrs
temperature, cooled
filtrationfiltered
washThe residue was washed with water and with acetone
customRecrystallization from DMF

출처 및 근거

ORD 기록: ord-15d3af4e6b18494ebd91db1be938a377
출처 데이터셋: uspto-grants-1978_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04066655

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참가 물질

반응물 1

HCID 12736922HCID 12736922, 화합물

생성물 1

HCID 12736925HCID 12736925, 화합물수율 87.5%

시약·촉매·용매 1

HCID 313Hydrochloric Acid용매

실험 절차

후처리

temperaturewas refluxed under nitrogen for 15 hrs
temperature, cooled
filtrationfiltered
washThe residue was washed with water and with acetone
customRecrystallization from DMF

출처 및 근거

ORD 기록: ord-15d3af4e6b18494ebd91db1be938a377
출처 데이터셋: uspto-grants-1978_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04066655

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불러오는 중…