HCID 21388034, 화합물 → HCID 21388032, 화합물
반응식
[C:1]([N:5]1[CH2:9][CH:8]([CH2:10][O:11][C:12]2[C:21]3[C:16](=[CH:17][CH:18]=[C:19]([Cl:22])[CH:20]=3)[C:15]([CH3:23])=[CH:14][N:13]=2)[O:7]C1C1C=CC=CC=1)([CH3:4])([CH3:3])[CH3:2]>Cl>[OH:7][CH:8]([CH2:9][NH:5][C:1]([CH3:4])([CH3:3])[CH3:2])[CH2:10][O:11][C:12]1[C:21]2[C:16](=[CH:17][CH:18]=[C:19]([Cl:22])[CH:20]=2)[C:15]([CH3:23])=[CH:14][N:13]=1참가 물질
3
실험 절차
1 g of 1-(3-tert.-Butyl-2-phenyl-5-oxazolidinyl-methoxy)-7-chloro-4-methylisoquinoline is heated to 80° in 10 ml of 1N hydrochloric acid for 10 minutes. The reaction mixture is extracted with ether. The ethereal phase is discarded and the aqueous phase worked up to yield the title compound in free base form. M.p. 116°-117°.
후처리
- extractionThe reaction mixture is extracted with ether
출처 및 근거
- ORD 기록
- ord-745197a7ef254b54a06f2dcd24e6ae9a
- 출처 데이터셋
- uspto-grants-1978_01
- 특허 번호
- US04067873
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