Ethylamine → N-Ethyl-1-naphthalenamine

HRID 1833968

반응식

HRID 1833968 반응식
[C:1]1(O)[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.P(OC1C=CC=CC=1)(OC1C=CC=CC=1)OC1C=CC=CC=1.[CH2:34]([NH2:36])[CH3:35].[OH-].[Na+]>>[CH2:34]([NH:36][C:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1)[CH3:35]

참가 물질

5

반응물 4

HCID 6341EthylamineHCID 70051-NaphtholHCID 7540Triphenyl phosphiteHCID 14798Sodium Hydroxide

생성물 1

HCID 67043N-Ethyl-1-naphthalenamine수율 90%

실험 절차

288 parts of α-naphthol, 10 parts of triphenyl phosphite and 100 parts of ethylamine gas are heated for 20 hours at 240° C, whilst stirring. After the mixture has cooled, it is next stirred for 20 minutes at 70° C with 1,000 parts of 2.5 percent strength by weight aqueous sodium hydroxide solution. The organic phase is separated off, washed with 2,000 parts of water at 30° C, again separated off and distilled. 308 parts of N-ethyl-α-naphthylamine boiling at 119° - 120° C/0.1 mm Hg are obtained, corresponding to a yield of 90% of theory.

후처리

  1. temperatureAfter the mixture has cooled
  2. customThe organic phase is separated off
  3. washwashed with 2,000 parts of water at 30° C
  4. customagain separated off
  5. distillationdistilled

출처 및 근거

ORD 기록
ord-668db951f10044cdb9cdab62885f255a
출처 데이터셋
uspto-grants-1978_01
특허 번호
US04067903

연결된 노트

불러오는 중…