Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(3-Chlorophenyl)boronic acid → Ethyl 2-{4-[3-(3-chlorophenyl)phenoxy]phenyl}-1-cyclohexylbenzimidazole-5-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (3-Chlorophenyl)boronic acid | HCID 2734323 | — |
| 반응물 | Ethyl 2-[4-(3-bromophenoxy)phenyl]-1-cyclohexylbenzimidazole-5-carboxylate | HCID 9914616 | — |
| 생성물 | Ethyl 2-{4-[3-(3-chlorophenyl)phenoxy]phenyl}-1-cyclohexylbenzimidazole-5-carboxylate | HCID 10231019 | 85.6% |
반응 단계
Ethyl 2-[4-(3-bromophenoxy)phenyl]-1-cyclohexylbenzimidazole-5-carboxylate (65 g) obtained in Example 1 and 3-chlorophenylboronic acid (23 g) were treated in the same manner as in Example 5 to give the title compound (59 g, yield 85%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06770666B2 |
| 출처 데이터셋 | uspto-grants-2004_08 |
| ORD ID | ord-aaf9765864a54fc4992ee6b11ecf0c70 |
| 출처 메모 | uspto-grants-2004_08 |