Hydrochloric Acid → HCID 22678561, 화합물

HRID 1837688노트

반응식

HRID 1837688 반응식
C(OC([N:8]1[CH2:13][CH2:12][CH:11]([CH2:14][CH2:15][C:16]2[S:17][CH:18]=[CH:19][C:20]=2[S:21]([CH3:24])(=[O:23])=[O:22])[CH2:10][CH2:9]1)=O)(C)(C)C.[ClH:25]>C(OCC)(=O)C>[ClH:25].[CH3:24][S:21]([C:20]1[CH:19]=[CH:18][S:17][C:16]=1[CH2:15][CH2:14][CH:11]1[CH2:12][CH2:13][NH:8][CH2:9][CH2:10]1)(=[O:22])=[O:23]

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 226783201-Tert-butoxycarbonyl-4-[2-(3-methylsulfonyl-2-thienyl)ethyl]piperidine

생성물 1

HCID 22678561HCID 22678561, 화합물

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매2회

실험 절차

11.1 g of 1-tert-butoxycarbonyl-4-[2-(3-methylsulfonyl-2-thienyl)ethyl]piperidine was dissolved in 100 ml of ethyl acetate, 100 ml of an ethyl acetate solution of 4N hydrochloric acid was added thereto, and the mixture was further stirred at room temperature for 2 hours. The resulting crystals were collected by filtration, washed with ethyl acetate, and air-dried, to give 7.92 g of the title compound as colorless crystals.

후처리

  1. filtrationThe resulting crystals were collected by filtration
  2. washwashed with ethyl acetate
  3. customair-dried

출처 및 근거

ORD 기록
ord-e6d41132ce9540478b98fcd511322d1d
출처 데이터셋
uspto-grants-2004_08
특허 번호
US06784192B2

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