3-Fluorosalicylaldehyde → 2-Fluoro-6-(hydroxymethyl)phenol

HRID 1838748노트

반응식

[BH4-].[Na+].[F:3][C:4]1[C:5]([OH:12])=[C:6]([CH:9]=[CH:10][CH:11]=1)[CH:7]=[O:8]>>[F:3][C:4]1[CH:11]=[CH:10][CH:9]=[C:6]([CH2:7][OH:8])[C:5]=1[OH:12]

참가 물질

반응물 2

HCID 5877883-Fluorosalicylaldehyde

HCID 4311764Sodium borohydride

생성물 1

HCID 187554072-Fluoro-6-(hydroxymethyl)phenol

실험 절차

In an analogous manner to that described in (β) 3-fluoro-2-hydroxy-benzaldehyde was reduced by sodium borohydride to yield 2-fluoro-6-hydroxymethyl-phenol as a white solid; MS: 142 (M)+.

출처 및 근거

ORD 기록: ord-25661d9f8851403c9eda7e668cef5ca0
출처 데이터셋: uspto-grants-2004_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06673931B2

반응 노트

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