Isobutyl chloride → 5,6-bis(4-Methoxyphenyl)-4-cyano-2-isobutyl-2H-pyridazin-3-one

HRID 1840267

반응식

[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:14]([C:15]3[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=3)=[N:13][NH:12][C:11](=[O:23])[C:10]=2[C:24]#[N:25])=[CH:5][CH:4]=1.[CH2:26](Cl)[CH:27]([CH3:29])[CH3:28]>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:14]([C:15]3[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=3)=[N:13][N:12]([CH2:26][CH:27]([CH3:29])[CH3:28])[C:11](=[O:23])[C:10]=2[C:24]#[N:25])=[CH:5][CH:4]=1

참가 물질

반응물 2

HCID 10554Isobutyl chloride

HCID 126885835,6-bis(4-methoxyphenyl)-4-cyano-2H-pyridazin-3-one

생성물 1

HCID 155185085,6-bis(4-Methoxyphenyl)-4-cyano-2-isobutyl-2H-pyridazin-3-one수율 71.8%

실험 절차

Using 5,6-bis(4-methoxyphenyl)-4-cyano-2H-pyridazin-3-one and isobutyl chloride as starting materials, the procedures of Example 1 were repeated likewise, whereby the title compound was obtained in a yield of 71.8%.

출처 및 근거

ORD 기록: ord-92dd18123861424697b67ed9628c434a
출처 데이터셋: uspto-grants-2004_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06680316B1

연결된 노트

불러오는 중…