Trifluoroacetic anhydride → HCID 21866554, 화합물

HRID 1840718노트

반응식

[NH2:1][CH2:2][C:3]1[S:7][C:6]([C:8]#[N:9])=[C:5](C)[CH:4]=1.[Cl:11]C1C=CSC=1C#N.[Cl:19]C1C=CSC=1C(N)=O.FC(F)(F)C(OC(=O)C(F)(F)F)=O>>[ClH:11].[NH2:1][CH2:2][C:3]1[S:7][C:6]([C:8]#[N:9])=[C:5]([Cl:19])[CH:4]=1

참가 물질

반응물 4

HCID 9845Trifluoroacetic anhydride

HCID 27574383-Chloro-2-cyanothiophene

HCID 28080883-Chloro-2-thiophenecarboxamide

HCID 218664655-(Aminomethyl)-3-methyl-2-thiophenecarbonitrile

생성물 1

HCID 21866554HCID 21866554, 화합물

실험 절차

This compound was prepared analogously to 5-aminomethyl-3-methylthiophene-2-carbonitrile, the 3-chloro-2-cyanothiophene used having been prepared by dehydrating 3-chlorothiophene-2-carboxamide (substances commercially available) with trifluoroacetic anhydride.

출처 및 근거

ORD 기록: ord-9b19568387a34e01b9eb355fbdaed6d7
출처 데이터셋: uspto-grants-2004_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06683055B1

반응 노트

불러오는 중…