Pyrrolidine → 6-Bromo-2-(pyrrolidin-1-YL)-[1,2,4]triazolo[1,5-A]pyridine

HRID 1844474노트

반응식

HRID 1844474 반응식
N1CCCC1.[Br:6][C:7]1[CH:8]=[CH:9][C:10]2[N:11]([N:13]=[C:14]([N:16]3[CH2:21][CH2:20]O[CH2:18][CH2:17]3)[N:15]=2)[CH:12]=1>>[Br:6][C:7]1[CH:8]=[CH:9][C:10]2[N:11]([N:13]=[C:14]([N:16]3[CH2:21][CH2:20][CH2:18][CH2:17]3)[N:15]=2)[CH:12]=1

참가 물질

3

반응물 2

HCID 31268PyrrolidineHCID 717438774-(6-Bromo-[1,2,4]triazolo[1,5-A]pyridin-2-YL)morpholine

생성물 1

HCID 717439856-Bromo-2-(pyrrolidin-1-YL)-[1,2,4]triazolo[1,5-A]pyridine

실험 절차

Using pyrrolidine, this compound was prepared following the same method as for the synthesis of 6-bromo-2-morpholin-4-yl-[1,2,4]triazolo[1,5-a]pyridine Off white solid (1.0 g, 41%). MS: m/z=268 (M+H+).

후처리

  1. customthis compound was prepared

출처 및 근거

ORD 기록
ord-f92d21bc453948b2b03fa3d5c2aa506e
출처 데이터셋
uspto-grants-2015_02
특허 번호
US08946427B2

반응 노트

불러오는 중…