Water → 8-(1-(1-((Tert-butyldimethylsilyl)oxy)-4-methyl-1,3-dihydroisobenzofuran-5-yl)-1-hydroxy-2-methylpropan-2-yl)-2-(4-methyl-5-oxo-2,5-dihydrofuran-3-yl)-2,8-diazaspiro[4.5]decan-1-one

반응식

[Si:1]([O:8][CH:9]1[C:17]2[C:12](=[C:13]([CH3:34])[C:14]([CH:18]([OH:33])[C:19]([N:22]3[CH2:32][CH2:31][C:25]4([C:29](=[O:30])[NH:28][CH2:27][CH2:26]4)[CH2:24][CH2:23]3)([CH3:21])[CH3:20])=[CH:15][CH:16]=2)[CH2:11][O:10]1)([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2].FC(F)(F)S(O[C:41]1[CH2:42][O:43][C:44](=[O:47])[C:45]=1[CH3:46])(=O)=O.C(=O)([O-])[O-].[K+].[K+].CC1(C)C2C(=C(P(C3C=CC=CC=3)C3C=CC=CC=3)C=CC=2)OC2C(P(C3C=CC=CC=3)C3C=CC=CC=3)=CC=CC1=2.O>C1(C)C=CC=CC=1.C([O-])(=O)C.[Pd+2].C([O-])(=O)C>[Si:1]([O:8][CH:9]1[C:17]2[C:12](=[C:13]([CH3:34])[C:14]([CH:18]([OH:33])[C:19]([N:22]3[CH2:23][CH2:24][C:25]4([C:29](=[O:30])[N:28]([C:41]5[CH2:42][O:43][C:44](=[O:47])[C:45]=5[CH3:46])[CH2:27][CH2:26]4)[CH2:31][CH2:32]3)([CH3:21])[CH3:20])=[CH:15][CH:16]=2)[CH2:11][O:10]1)([C:4]([CH3:5])([CH3:6])[CH3:7])([CH3:2])[CH3:3]