Phthalic Anhydride → N-Methylphthalimide

HRID 1855930노트

반응식

HRID 1855930 반응식
O([C:8]1[CH:9]=[C:10]2[C:15](=[O:16])[N:14]([CH3:17])[C:12](=[O:13])[C:11]2=[CH:18][CH:19]=1)C1C=CC=CC=1.C1(=O)OC(=O)C2=CC=CC=C12>>[CH3:17][N:14]1[C:12](=[O:13])[C:11]2=[CH:18][CH:19]=[CH:8][CH:9]=[C:10]2[C:15]1=[O:16]

참가 물질

3

반응물 2

HCID 6811Phthalic AnhydrideHCID 8215562-methyl-5-phenoxyisoindole-1,3-dione

생성물 1

HCID 11074N-Methylphthalimide수율 46%

실험 절차

The above results show that an exchange occurred between 4-phenoxy-N-methylphthalimide and phthalic anhydride, resulting in a 46% yield of N-methylphthalimide and a 64% yield of 4-phenoxyphthalic anhydride or acid. This conversion of 4-phenoxy-N-methylphthalimide to 4-phenoxyphthalic anhydride was achieved in a direct manner without any requirement for converting the 4-phenoxy-N-methylphthalimide to the corresponding hydrazide or the base hydrolysis thereof, resulting in the production of metal salt requiring the neutralization and heating of the resulting phthalic acid.

후처리

  1. customThe above results

출처 및 근거

ORD 기록
ord-796184338a7c4165a53017e35c02ff7c
출처 데이터셋
uspto-grants-1980_08
특허 번호
US04217281

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