Acetic Acid → HCID 22125747, 화합물

HRID 1858040노트

반응식

HRID 1858040 반응식
[OH:1][C:2]1[CH:3]=[C:4]([CH2:10][CH2:11][CH2:12][CH2:13][C:14]([OH:16])=[O:15])[CH:5]=[CH:6][C:7]=1[O:8][CH3:9].[CH2:17]1N2CN3CN(C2)CN1C3.Cl.[OH2:28].[C:29](O)(=[O:31])C>>[CH:17]([C:3]1[C:2]([OH:1])=[C:7]([O:8][CH3:9])[CH:6]=[C:5]([CH:29]=[O:31])[C:4]=1[CH2:10][CH2:11][CH2:12][CH2:13][C:14]([OH:16])=[O:15])=[O:28]

참가 물질

6

반응물 5

HCID 176Acetic AcidHCID 313Hydrochloric AcidHCID 962WaterHCID 4101HexamethylenetetramineHCID 2693075-(3-Hydroxy-4-methoxyphenyl)pentanoic acid

생성물 1

HCID 22125747HCID 22125747, 화합물

실험 절차

5-(3-Hydroxy-4-methoxyphenyl)pentanoic acid (8 g) and hexamethylenetetramine (10 g) in acetic acid (150 ml) were heated under reflux over night. 70 ml 6 M Hydrochloric acid was added to the reaction mixture and it was refluxed for half an hour. The mixture was poured into water and extracted with dichloromethane. The organic phase was evaporated in vacuo and the residue triturated with diethyl ether. Yield 3.04 g.

후처리

  1. temperatureunder reflux over night
  2. temperaturewas refluxed for half an hour
  3. extractionextracted with dichloromethane
  4. customThe organic phase was evaporated in vacuo
  5. customthe residue triturated with diethyl ether

출처 및 근거

ORD 기록
ord-f87af0678acd4e1ea86614ad9164451c
출처 데이터셋
uspto-grants-2000_11
특허 번호
US06150412

반응 노트

불러오는 중…