4-Methyl-1-penten-3-ol → 1-Furan-3-yl-4-methyl-pentan-3-one
반응식
Br[C:2]1[CH:6]=[CH:5][O:4][CH:3]=1.[CH3:7][CH:8]([CH3:13])[CH:9]([OH:12])[CH:10]=[CH2:11].C(=O)(O)[O-].[Na+]>[Cl-].C([N+](CCCC)(CCCC)CCCC)CCC.C([O-])(=O)C.[Pd+2].C([O-])(=O)C.CN(C=O)C>[O:4]1[CH:5]=[CH:6][C:2]([CH2:11][CH2:10][C:9](=[O:12])[CH:8]([CH3:13])[CH3:7])=[CH:3]1참가 물질
7
실험 절차
The title compound was prepared according to General Method 4a using 3-bromofuran (17 mmol), 4-methyl-1-penten-3-ol (25.5 mmol), tetrabutyl ammonium chloride (17 mmol), sodium bicarbonate (42.5 mmol), DMF (15 mL), and palladium acetate (0.9 mmol). The title compound was flash chromatographed eluting with EtOAc:hexane (5:95 to 10:90).
후처리
- customThe title compound was prepared
- customchromatographed
- washeluting with EtOAc:hexane (5:95 to 10:90)
출처 및 근거
- ORD 기록
- ord-4a68efe0000c4780a8c10c228b8e8dab
- 출처 데이터셋
- uspto-grants-2003_03
- 특허 번호
- US06528510B1
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