Sodium Hydroxide → 4'-Dimethoxymethylbiphenyl-4-carboxylic acid

HRID 1860008노트

반응식

[CH3:1][O:2][CH:3]([O:20][CH3:21])[C:4]1[CH:9]=[CH:8][C:7]([C:10]2[CH:15]=[CH:14][C:13]([C:16]([O:18]C)=[O:17])=[CH:12][CH:11]=2)=[CH:6][CH:5]=1.[OH-].[Na+]>>[CH3:21][O:20][CH:3]([O:2][CH3:1])[C:4]1[CH:5]=[CH:6][C:7]([C:10]2[CH:15]=[CH:14][C:13]([C:16]([OH:18])=[O:17])=[CH:12][CH:11]=2)=[CH:8][CH:9]=1

참가 물질

반응물 2

HCID 14798Sodium Hydroxide

HCID 18625704Methyl 4'-dimethoxymethylbiphenyl-4-carboxylate

생성물 1

HCID 186256964'-Dimethoxymethylbiphenyl-4-carboxylic acid수율 100.1%

실험 절차

In a similar manner to that described in Example 2, a reaction was carried out using methyl 4′-dimethoxymethylbiphenyl-4-carboxylate (1.89 g), which is the product of Reference example 11(a), and aqueous sodium hydroxide (1N, 9.90 ml) and the reaction mixture was treated to afford the desired compound (1.80 g) as colorless crystals.

후처리

additionthe reaction mixture was treated

출처 및 근거

ORD 기록: ord-082edb70c69f4c4d9be86f4b0f653062
출처 데이터셋: uspto-grants-2003_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06528525B1

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