Sodium Hydroxide → 3'-Dimethoxymethylbiphenyl-4-carboxylic acid

반응식

[CH3:1][O:2][CH:3]([O:20][CH3:21])[C:4]1[CH:5]=[C:6]([C:10]2[CH:15]=[CH:14][C:13]([C:16]([O:18]C)=[O:17])=[CH:12][CH:11]=2)[CH:7]=[CH:8][CH:9]=1.[OH-].[Na+]>>[CH3:21][O:20][CH:3]([O:2][CH3:1])[C:4]1[CH:5]=[C:6]([C:10]2[CH:15]=[CH:14][C:13]([C:16]([OH:18])=[O:17])=[CH:12][CH:11]=2)[CH:7]=[CH:8][CH:9]=1

참가 물질

반응물 2

HCID 14798Sodium Hydroxide

HCID 18626005HCID 18626005, 화합물

생성물 1

HCID 186258743'-Dimethoxymethylbiphenyl-4-carboxylic acid수율 85.3%

실험 절차

In a similar manner to that described in Example 2, a reaction was carried out using methyl 3′-dimethoxymethylbiphenyl-4-carboxylate (1.91 g), which is the product of Reference example 14(b), and aqueous sodium hydroxide (1N, 10.0 ml) and the reaction mixture was treated to afford the desired compound (1.55 g) as colorless crystals.

후처리

additionthe reaction mixture was treated

출처 및 근거

ORD 기록: ord-7b122282a3904a01a107eec63ab3478a
출처 데이터셋: uspto-grants-2003_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06528525B1

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