Sodium Hydroxide → 4-(2-hydroxyphenyl)benzoic Acid

HRID 1860020노트

반응식

HRID 1860020 반응식
[OH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:13]=[CH:12][C:11]([C:14]([O:16]C)=[O:15])=[CH:10][CH:9]=1.[OH-].[Na+]>>[OH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:13]=[CH:12][C:11]([C:14]([OH:16])=[O:15])=[CH:10][CH:9]=1

참가 물질

3

반응물 2

HCID 14798Sodium HydroxideHCID 45648562-(4-Methoxycarbonylphenyl)phenol

생성물 1

HCID 106562444-(2-hydroxyphenyl)benzoic Acid수율 92.9%

실험 절차

In a similar manner to that described in Example 2, a reaction was carried out using methyl 2′-hydroxybiphenyl-4-carboxylate (498 mg) and aqueous sodium hydroxide (1N, 4.81 ml) and the reaction mixture was treated to afford the title compound (434 mg) as colorless crystals.

후처리

  1. additionthe reaction mixture was treated

출처 및 근거

ORD 기록
ord-340d1ef9824643168ccac76c4eb8a5ab
출처 데이터셋
uspto-grants-2003_03
특허 번호
US06528525B1

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