Hydrochloric Acid → HCID 131723149, 화합물

HRID 1862712노트

반응식

HRID 1862712 반응식
C(OC([N:8]1[CH2:13][CH2:12][CH:11]([C:14]2[N:18]([CH2:19][CH3:20])[N:17]=[C:16]([CH2:21][CH3:22])[C:15]=2[CH3:23])[CH2:10][CH2:9]1)=O)(C)(C)C.[ClH:24]>CO>[ClH:24].[ClH:24].[CH2:19]([N:18]1[C:14]([CH:11]2[CH2:12][CH2:13][NH:8][CH2:9][CH2:10]2)=[C:15]([CH3:23])[C:16]([CH2:21][CH3:22])=[N:17]1)[CH3:20]

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 21912727HCID 21912727, 화합물

생성물 1

HCID 131723149HCID 131723149, 화합물수율 92%

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

A solution of 1-(t-butoxycarbonyl)-4-(1,3-diethyl-4-methyl-(1H)-pyrazol-5-yl)piperidine (348 mg) (from Step E) in 2.5 N HCl in methanol was stirred at rt for 16 h. The solution was concentrated and the resulting solid was suspended in ethyl acetate, filtered and dried to afford 293 mg (92%) of the title compound.

후처리

  1. concentrationThe solution was concentrated
  2. filtrationfiltered
  3. customdried

출처 및 근거

ORD 기록
ord-3936394c7454453fa5734d1167b731a0
출처 데이터셋
uspto-grants-2003_03
특허 번호
US06538002B1

반응 노트

불러오는 중…