Hydrochloric Acid → HCID 68523413, 화합물
반응식
[O:1]=[C:2]1[C:7]2[N:8]=[C:9]([C:12]([F:15])([F:14])[F:13])[N:10]=[CH:11][C:6]=2[CH2:5][CH2:4][N:3]1C(OC(C)(C)C)=O.Cl>O1CCOCC1>[F:15][C:12]([F:13])([F:14])[C:9]1[N:10]=[CH:11][C:6]2[CH2:5][CH2:4][NH:3][C:2](=[O:1])[C:7]=2[N:8]=1참가 물질
4
실험 절차
Approximately 485 mg (1.53 mmol) of tert-butyl 8-oxo-2-(trifluoromethyl)-5,8-dihydropyrido[3,4-d]pyrimidine-7(6H)-carboxylate was treated with 10 mL of 4M HCl in anhydrous dioxane, and the solution was stirred at room temperature for 0.5 h, then concentrated to dryness. The residue was washed with diethyl ether and dried to give the title compound as a white solid. LC-MS 218 (M+1).
후처리
- concentrationconcentrated to dryness
- washThe residue was washed with diethyl ether
- customdried
출처 및 근거
- ORD 기록
- ord-03cd092c21e3479c8be45433c6e5e74e
- 출처 데이터셋
- uspto-grants-2009_12
- 특허 번호
- US07625888B2
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