O-Methylhydroxylamine → 5-Hydroxymethyl-2-(6-methoxyamino-purin-9-yl)-3-methyl-tetrahydro-furan-3,4-diol

HRID 1865778

반응식

[O:1]([NH2:3])[CH3:2].Cl[C:5]1[N:13]=[CH:12][N:11]=[C:10]2[C:6]=1[N:7]=[CH:8][N:9]2[C@@H:14]1[O:20][C@H:19]([CH2:21][OH:22])[C@@H:17]([OH:18])[C@@:15]1([CH3:23])[OH:16]>>[CH3:23][C@@:15]1([OH:16])[C@H:17]([OH:18])[C@@H:19]([CH2:21][OH:22])[O:20][C@H:14]1[N:9]1[CH:8]=[N:7][C:6]2[C:10]1=[N:11][CH:12]=[N:13][C:5]=2[NH:3][O:1][CH3:2]

참가 물질

반응물 2

HCID 4113O-Methylhydroxylamine

HCID 10590378(2R,3R,4R,5R)-2-(6-Chloro-9H-purin-9-yl)-5-(hydroxymethyl)-3-methyltetrahydrofuran-3,4-diol

생성물 1

HCID 52734975-Hydroxymethyl-2-(6-methoxyamino-purin-9-yl)-3-methyl-tetrahydro-furan-3,4-diol

실험 절차

The above compound was synthesized from methoxylamine and 6-chloro-9-(2′-C-methyl-β-D-ribofuranosyl)purine as described in Example 1, Step 3.

출처 및 근거

ORD 기록: ord-b7f04bce87ae4afc9a8113bc1a8c7eea
출처 데이터셋: uspto-grants-2009_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07629320B2

연결된 노트

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