Hydrochloric Acid → 3,4-Diphenyl-1,2,5-thiadiazole-1,1-dioxide

HRID 18709

반응식

HRID 18709 반응식
Cl.[C:2]1([C:8]([C:10]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=O)=O)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[S:18]([NH2:22])([NH2:21])(=[O:20])=[O:19]>CO>[C:2]1([C:8]2[C:10]([C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)=[N:22][S:18](=[O:20])(=[O:19])[N:21]=2)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

5

반응물 3

HCID 313Hydrochloric AcidHCID 8651BenzilHCID 82267Sulfamide

생성물 1

HCID 110001093,4-Diphenyl-1,2,5-thiadiazole-1,1-dioxide수율 84,416%

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

Hydrogen chloride is bubbled through a solution of benzil (24 g, 0.11 mmol) and sulfamide (11 g, 0.11 mmol) in methanol (120 mL) for 2 h followed by heating to reflux for 2 h. The reaction mixture is cooled to RT, and the precipitate that formed is filtered to give 25.1 g of the product 14.

후처리

  1. temperatureby heating
  2. temperatureto reflux for 2 h
  3. customthe precipitate that formed
  4. filtrationis filtered

출처 및 근거

ORD 기록
ord-569fc833732c40199d9273c5321e5ed8
출처 데이터셋
uspto-grants-2010_06
특허 번호
US07741493B2

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