Bromine → HCID 22597763, 화합물

HRID 1872706노트

반응식

HRID 1872706 반응식
[CH3:1][O:2][C:3]1[CH:11]=[C:10]([CH:12]([CH3:14])[CH3:13])[CH:9]=[CH:8][C:4]=1[C:5]([OH:7])=[O:6].C(C1C=CC(C(O)=O)=C(OC)C=1)(C)(C)C.[Br:30]Br>C(Cl)(Cl)Cl>[Br:30][C:9]1[C:10]([CH:12]([CH3:14])[CH3:13])=[CH:11][C:3]([O:2][CH3:1])=[C:4]([CH:8]=1)[C:5]([OH:7])=[O:6]

참가 물질

5

반응물 3

HCID 24408BromineHCID 126137372-Methoxy-4-(propan-2-yl)benzoic acidHCID 126137394-tert-Butyl-2-methoxybenzoic acid

생성물 1

HCID 22597763HCID 22597763, 화합물

시약·촉매·용매 1

HCID 6212Chloroform용매2회

실험 절차

To a solution of 2-methoxy-4-iso-propyl benzoic acid (prepared in an analogous manner to Preparation 37, 4-tert-butyl-2-methoxy benzoic acid) (7.0 g, 36.0 mmol) in chloroform (100 ml) was added bromine (1.86 ml) in chloroform (20 ml) dropwise. The reaction was stirred at room temperature overnight. Evaporation in vacuo afforded an oil (9.27 g). m /z (CI): 275, 273 (MH+ ; 70%).

후처리

  1. customEvaporation in vacuo

출처 및 근거

ORD 기록
ord-19894fa651b54de497338116275ac609
출처 데이터셋
uspto-grants-2000_08
특허 번호
US06110934

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