Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Citric Acid → 3-bromo-4-(bromomethyl)benzoic Acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Citric Acid | HCID 311 | — |
| 반응물 | Azobisisobutyronitrile | HCID 6547 | — |
| 반응물 | N-bromobutanimide | HCID 67184 | — |
| 반응물 | 3-Bromo-4-methylbenzoic acid | HCID 82130 | — |
| 용매 | Carbon Tetrachloride | HCID 5943 | — |
| 생성물 | 3-bromo-4-(bromomethyl)benzoic Acid | HCID 11616314 | 43.9% |
반응 단계
3-Bromo-4-methylbenzoic acid (10 g), N-bromosuccinimide (8.7 g) and 2,2′-azobisisobutyronitrile (0.4 g) were suspended in carbon tetrachloride (50 ml) and then heated to reflux for 2 hours. The mixture was returned to room temperature and added a 15% aqueous solution of citric acid (20 ml), and stirred for some time. Resulting crystals were filtered and washed with the 15% aqueous solution of citric acid (20 ml), and then dried, to obtain 3-bromo-4-(bromomethyl)benzoic acid (6 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08304371B2 |
| 출처 데이터셋 | uspto-grants-2012_11 |
| ORD ID | ord-4f415148a749447e94cd2cc20e55e462 |
| 출처 메모 | uspto-grants-2012_11 |