Ethyl formate → N-(1-Methyl-2-thiophen-2-yl-ethyl)-formamide

반응식

[CH3:1][CH:2]([NH2:9])[CH2:3][C:4]1[S:5][CH:6]=[CH:7][CH:8]=1.[CH:10](OCC)=[O:11]>>[CH3:1][CH:2]([NH:9][CH:10]=[O:11])[CH2:3][C:4]1[S:5][CH:6]=[CH:7][CH:8]=1

참가 물질

반응물 2

HCID 8025Ethyl formate

HCID 64841332-(2-Aminopropyl)thiophene

생성물 1

HCID 64990444N-(1-Methyl-2-thiophen-2-yl-ethyl)-formamide

실험 절차

A solution of 5.9 g (33.4 mmol) 1-methyl-2-thiophen-2-yl-ethylamine in 34.8 ml (417.7 mmol) ethyl formate is refluxed for 16 hours. Then the mixture is cooled and evaporated to dryness i. vac.

후처리

temperatureThen the mixture is cooled
customevaporated to dryness i

출처 및 근거

ORD 기록: ord-eb1756aec0da40b2aba2bbccb88f8d1c
출처 데이터셋: uspto-grants-2012_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08309542B2

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