Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1876938생성일: 2026년 10월 26일
{2-Ethyl-5-[4-(trifluoromethyl)phenyl]-3-furyl}methanol → 2-Ethyl-5-[4-(trifluoromethyl)phenyl]-3-furaldehyde
https://huagongshe.com/reaction/1876938
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | {2-Ethyl-5-[4-(trifluoromethyl)phenyl]-3-furyl}methanol | HCID 23074480 | — |
| 촉매 | HCID 178418406 | HCID 178418406 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 2-Ethyl-5-[4-(trifluoromethyl)phenyl]-3-furaldehyde | HCID 23074355 | 24.6% |
반응 단계
A suspension of {2-ethyl-5-[4-(trifluoromethyl)phenyl]-3-furyl}methanol (2.7 g) and manganese dioxide (6.8 g) in diethyl ether (20 mL) and tetrahydrofuran (20 mL) was stirred overnight at 40° C. Manganese dioxide was filtered off, and the filtrate was evaporated under reduced pressure. The residue was purified by silica gel chromatography (5% ethyl acetate/hexane to 20% ethyl acetate/hexane), and crystallized from ethyl acetate/hexane to give the title compound (0.66 g, 24%) as a yellow solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US08309580B2 |
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| 출처 데이터셋 | uspto-grants-2012_11 |
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| ORD ID | ord-702d166f9b8142d3b86b750a9e79e101 |
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| 출처 메모 | uspto-grants-2012_11 |
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