Potassium Hydroxide → HCID 137068883, 화합물
반응식
Cl.[NH2:2][OH:3].[OH-].[K+].[Cl:6][CH2:7][C:8]([NH:10][C:11]1[CH:12]=[N:13][C:14]([C:17]#[N:18])=[CH:15][CH:16]=1)=[O:9]>CO>[Cl:6][CH2:7][C:8]([NH:10][C:11]1[CH:12]=[N:13][C:14]([C:17](=[N:2][OH:3])[NH2:18])=[CH:15][CH:16]=1)=[O:9]참가 물질
5
실험 절차
Hydroxylamine hydrochloride (0.16 g, 2.3 mmol) was added to a solution of potassium hydroxide (0.152 g, 2.3 mmol) in methanol and the mixture was stirred for 30 minutes and filtered. To the filtrate, compound of example 3 (0.3 g, 1.53 mmol) was added and reaction mixture was refluxed for 4 hours. After completion of reaction the mixture was cooled, concentrated and triturated with diethyl ether to obtain the title compound.
후처리
- filtrationfiltered
- customreaction mixture
- temperaturewas refluxed for 4 hours
- customAfter completion of reaction the mixture
- temperaturewas cooled
- concentrationconcentrated
- customtriturated with diethyl ether
출처 및 근거
- ORD 기록
- ord-c404df0c24084c34841264fc935271b0
- 출처 데이터셋
- uspto-grants-2012_11
- 특허 번호
- US08314103B2
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