Chlorodifluoroacetic acid → 4-Nitrosotetrahydro-2H-pyran-4-yl 2-chloro-2,2-difluoroacetate

HRID 1879798

반응식

HRID 1879798 반응식
[O:1]1[CH2:6][CH2:5][C:4](=[N:7][OH:8])[CH2:3][CH2:2]1.C([O-])(=O)C.C([O-])(=O)C.C([O-])(=O)C.C([O-])(=O)C.[Pb+4].[Cl:26][C:27]([F:32])([F:31])[C:28]([OH:30])=[O:29]>>[Cl:26][C:27]([F:32])([F:31])[C:28]([O:30][C:4]1([N:7]=[O:8])[CH2:5][CH2:6][O:1][CH2:2][CH2:3]1)=[O:29]

참가 물질

4

반응물 3

HCID 66154Chlorodifluoroacetic acidHCID 12298558N-(oxan-4-ylidene)hydroxylamineHCID 178418268HCID 178418268, 화합물

생성물 1

HCID 444791424-Nitrosotetrahydro-2H-pyran-4-yl 2-chloro-2,2-difluoroacetate

실험 절차

4-Nitrosotetrahydro-2H-pyran-4-yl 2-chloro-2,2-difluoroacetate was prepared from tetrahydro-pyran-4-one oxime, lead tetraacetate and chlorodifluoroacetic acid using conditions of General Method 3. 1H NMR (360 MHz, chloroform-d) δ 4.06-4.23 (2H, m), 3.52-3.86 (2H, m), 2.27-2.70 (2H, m), 1.72-2.07 (2H, m).

출처 및 근거

ORD 기록
ord-7a6c5527225440c28a5f2f59810a2bd2
출처 데이터셋
uspto-grants-2012_11
특허 번호
US08318705B2

연결된 노트

불러오는 중…