Acetic Anhydride → 2-Acetamido-8-methoxytetralin

반응식

[CH3:1][O:2][C:3]1[CH:4]=[CH:5][CH:6]=[C:7]2[C:12]=1[CH2:11][CH:10]([NH2:13])[CH2:9][CH2:8]2.[C:14](OC(=O)C)(=[O:16])[CH3:15]>>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][CH:6]=[C:7]2[C:12]=1[CH2:11][CH:10]([NH:13][C:14](=[O:16])[CH3:15])[CH2:9][CH2:8]2

참가 물질

반응물 2

HCID 7918Acetic Anhydride

HCID 101979338-Methoxy-2-aminotetralin

생성물 1

HCID 30189202-Acetamido-8-methoxytetralin수율 69%

실험 절차

Using a procedure similar to that described in Example 1, 0.30 g of 8-methoxy-2-amino-tetralin yielded 0.23 g (69%) of 8-methoxy-2-acetamido-tetralin following treatment with acetic anhydride.

출처 및 근거

ORD 기록: ord-53514a38a6bd40ab9f67fb622f638756
출처 데이터셋: uspto-grants-1992_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05151446

반응 노트

불러오는 중…