Iodoethane → 4-Ethyl-6-(piperidin-4-yloxy)-isoquinoline
반응식
[NH:1]1[CH2:6][CH2:5][CH:4]([O:7][C:8]2[CH:9]=[C:10]3[C:15](=[CH:16][CH:17]=2)[CH:14]=[N:13][CH:12]=[C:11]3[CH2:18][CH2:19]CC(F)(F)F)[CH2:3][CH2:2]1.C(I)C>>[CH2:18]([C:11]1[C:10]2[C:15](=[CH:16][CH:17]=[C:8]([O:7][CH:4]3[CH2:5][CH2:6][NH:1][CH2:2][CH2:3]3)[CH:9]=2)[CH:14]=[N:13][CH:12]=1)[CH3:19]참가 물질
3
실험 절차
The compound 266 was synthesized in a similar fashion as described for compound 90, using ethyl iodide. LCMS Method # 1, retention time 0.98 min, detected mass 257.31 [M+H]+
출처 및 근거
- ORD 기록
- ord-e7342b8afa3349ec82c9f3b3e1a41fd2
- 출처 데이터셋
- uspto-grants-2013_08
- 특허 번호
- US08501736B2
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