Hydrochloric Acid → HCID 68412119, 화합물

HRID 1887745노트

반응식

HRID 1887745 반응식
[NH2:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:11]=1[NH:10][C:9](=[O:12])[CH:8]([NH:13]C(=O)C)[CH2:7]2.[ClH:17]>>[ClH:17].[ClH:17].[NH2:13][CH:8]1[CH2:7][C:6]2[C:11](=[C:2]([NH2:1])[CH:3]=[CH:4][CH:5]=2)[NH:10][C:9]1=[O:12]

참가 물질

3

반응물 2

HCID 313Hydrochloric AcidHCID 59620340HCID 59620340, 화합물

생성물 1

HCID 68412119HCID 68412119, 화합물

반응 조건

온도
110 °C

실험 절차

N-(8-Amino-2-oxo-1,2,3,4-tetrahydroquinolin-3-yl)acetamide (8.4 g) was added to concentrated hydrochloric acid (84 mL), and the mixture was heated at 110° C. for three hours while being stirred, followed by stirring under cooling on ice. The formed precipitates were recovered through filtration, and the thus-obtained solid was washed with ethanol, followed by drying, whereby the title compound (9.17 g) was yielded.

후처리

  1. stirringby stirring
  2. temperatureunder cooling on ice
  3. customThe formed precipitates
  4. filtrationwere recovered through filtration
  5. washthe thus-obtained solid was washed with ethanol
  6. customby drying

출처 및 근거

ORD 기록
ord-9e45c8415a57486b805f7f50f46222de
출처 데이터셋
uspto-grants-2013_08
특허 번호
US08501772B2

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