4-Carbamoylbenzoic acid → N-(7-Chloro-2-oxazol-2-yl-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-terephthal-amide

참여 물질

역할	이름	HCID	투입량
반응물	4-Carbamoylbenzoic acid	HCID 506057	—
반응물	3-aminomethyl-7-chloro-2-oxazol-2-yl-1-phenyl-1H-quinolin-4-one	HCID 71208332	—
생성물	N-(7-Chloro-2-oxazol-2-yl-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-terephthal-amide	HCID 71208768	—

반응 단계

N-(7-Chloro-2-oxazol-2-yl-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-terephthal-amide was prepared starting from intermediate A and 4-(aminocarbonyl)benzoic acid. 1H NMR (400 MHz, DMSO-d6) δ ppm 8.40 (t, J=4.50 Hz, 1H) 8.31 (d, J=8.59 Hz, 1H) 8.02 (br. s, 1H) 7.97 (d, J=0.78 Hz, 1H) 7.83-7.87 (m, 2H) 7.73-7.78 (m, 2H) 7.37-7.54 (m, 7H) 7.16 (d, J=0.78 Hz, 1H) 6.72 (d, J=1.56 Hz, 1H) 4.25 (d, J=4.30 Hz, 2H). MS calcd. for C27H19ClN4O4 [(M+H)+] 499.1, obsd. 499.

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US08501732B2
출처 데이터셋	uspto-grants-2013_08
ORD ID	ord-2c8178998d65439f9536359e55e53d4d
출처 메모	uspto-grants-2013_08