4-(4-Isopropylphenyl)butanoic acid → HCID 59409743, 화합물

HRID 1892093노트

반응식

HRID 1892093 반응식
[CH:1]([C:4]1[CH:9]=[CH:8][C:7]([CH2:10][CH2:11][CH2:12][C:13]([OH:15])=[O:14])=[CH:6][CH:5]=1)([CH3:3])[CH3:2]>C(O)(=O)C.O=[Pt]=O>[CH:1]([CH:4]1[CH2:9][CH2:8][CH:7]([CH2:10][CH2:11][CH2:12][C:13]([OH:15])=[O:14])[CH2:6][CH2:5]1)([CH3:3])[CH3:2]

참가 물질

4

반응물 1

HCID 3476744-(4-Isopropylphenyl)butanoic acid

생성물 1

HCID 59409743HCID 59409743, 화합물수율 107.9%

시약·촉매·용매 2

HCID 345198Adams' catalyst촉매HCID 176Acetic Acid용매

실험 절차

A suspension of compound 77 (1.0 g, 4.8 mmol) and 0.1 g of PtO2 in 50 mL of acetic acid was stirred under a H2 atmosphere (50 psi) at ambient temperature for 6 hours. After filtering and evaporating off the solvent, 1.1 g crude product was obtained. The compound was used directly in the next step without further purification. LC-MS m/z 211 (M−H+).

후처리

  1. filtrationAfter filtering
  2. customevaporating off the solvent

출처 및 근거

ORD 기록
ord-fc6f5632061a4f348c6ca76e3648c2a0
출처 데이터셋
uspto-grants-2013_08
특허 번호
US08507647B2

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