Hydrochloric Acid → HCID 178472456, 화합물

HRID 1893342노트

반응식

HRID 1893342 반응식
[CH2:1]([O:3][C:4]([C@H:6]1[CH2:11][CH2:10][C@H:9]([NH:12][NH:13]C(OC(C)(C)C)=O)[CH2:8][CH2:7]1)=[O:5])[CH3:2].O1CCOCC1.[ClH:27]>>[ClH:27].[CH2:1]([O:3][C:4]([C@H:6]1[CH2:11][CH2:10][C@H:9]([NH:12][NH2:13])[CH2:8][CH2:7]1)=[O:5])[CH3:2]

참가 물질

4

반응물 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 178472458HCID 178472458, 화합물

생성물 1

HCID 178472456HCID 178472456, 화합물

실험 절차

A solution of trans-4-(N′-tert-butoxycarbonyl-hydrazino)-cyclohexanecarboxylic acid ethyl ester (0.625 g, 2.18 mmol) in 4 M hydrogen chloride solution in 1,4-dioxane (5.5 ml, 22 mmol) was stirred at room temperature for 3 days. The precipitate was collected by filtration, washed with tert-butyl methyl ether and dried in vacuo to give the title compound as white solid in quantitative yield. MS m/e: 187 ([M+H]+).

후처리

  1. filtrationThe precipitate was collected by filtration
  2. washwashed with tert-butyl methyl ether
  3. customdried in vacuo

출처 및 근거

ORD 기록
ord-b4f698f46c0242bc853f152a02042e55
출처 데이터셋
uspto-grants-2013_08
특허 번호
US08513238B2

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