Methyl iodide → 1-(3-Fluoro-5-iodo-pyridin-2-yl)-3,4,4-trimethyl-imidazolidin-2-one

반응식

[F:1][C:2]1[C:3]([N:9]2[CH2:13][C:12]([CH3:15])([CH3:14])[NH:11][C:10]2=[O:16])=[N:4][CH:5]=[C:6]([I:8])[CH:7]=1.I[CH3:18]>>[F:1][C:2]1[C:3]([N:9]2[CH2:13][C:12]([CH3:14])([CH3:15])[N:11]([CH3:18])[C:10]2=[O:16])=[N:4][CH:5]=[C:6]([I:8])[CH:7]=1

참가 물질

반응물 2

HCID 6328Methyl iodide

HCID 575167531-(3-Fluoro-5-iodo-pyridin-2-yl)-4,4-dimethyl-imidazolidin-2-one

생성물 1

HCID 575167541-(3-Fluoro-5-iodo-pyridin-2-yl)-3,4,4-trimethyl-imidazolidin-2-one

실험 절차

The title compound, a yellow oil, MS: m/e=350.0 (M+H+), was prepared in accordance with the general method of Example 16 from 1-(3-fluoro-5-iodo-pyridin-2-yl)-4,4-dimethyl-imidazolidin-2-one (Example 110, step 1) and iodomethane.

출처 및 근거

ORD 기록: ord-d87fed95f1f14fb8b6aa761f53f6d247
출처 데이터셋: uspto-grants-2013_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08513273B2

반응 노트

불러오는 중…