Tetrahydrofuran → 1-[5-(4-Fluoro-phenylethynyl)-pyridin-2-yl]-4,4-dimethyl-pyrrolidin-2-one

반응식

[CH3:1][C:2]1([CH3:20])[CH2:6][N:5]([C:7]2[N:12]=[CH:11][C:10]([C:13]#[C:14][Si](C)(C)C)=[CH:9]N=2)[C:4](=[O:19])[CH2:3]1.[F:21][C:22]1[CH:27]=[CH:26][C:25](I)=[CH:24][CH:23]=1.[CH3:29]CN(CC)CC.CCCC[N+](CCCC)(CCCC)CCCC.[F-].C1COCC1>CN(C=O)C.C1C=CC(P(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1.C1C=CC(P(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1.Cl[Pd]Cl.[Cu]I>[F:21][C:22]1[CH:27]=[CH:26][C:25]([C:14]#[C:13][C:10]2[CH:9]=[CH:29][C:7]([N:5]3[CH2:6][C:2]([CH3:1])([CH3:20])[CH2:3][C:4]3=[O:19])=[N:12][CH:11]=2)=[CH:24][CH:23]=1