Dimethylformamide → (3-Methyl-but-3-enyloxymethyl)-benzene

HRID 1896967노트

반응식

HRID 1896967 반응식
[CH:1]1[CH:6]=[CH:5][C:4]([CH2:7]Br)=[CH:3][CH:2]=1.[H-].[Na+].CN([CH:14]=[O:15])C>>[CH3:5][C:4](=[CH2:3])[CH2:7][CH2:14][O:15][CH2:7][C:4]1[CH:5]=[CH:6][CH:1]=[CH:2][CH:3]=1

참가 물질

4

반응물 3

HCID 6228DimethylformamideHCID 7498Benzyl BromideHCID 24758Sodium hydride

생성물 1

HCID 11095166(3-Methyl-but-3-enyloxymethyl)-benzene

실험 절차

BnBr was added to the mixture of alcohol and NaH in DMF cooled in an ice bath. The mixture was stirred at room temperature overnight and the solid was filtered. The solvent was removed and the residue was purified by column chromatography to give compound 1.

후처리

  1. temperaturecooled in an ice bath
  2. filtrationthe solid was filtered
  3. customThe solvent was removed
  4. customthe residue was purified by column chromatography

출처 및 근거

ORD 기록
ord-c177285f9c834ac8b295e2a82883d8a5
출처 데이터셋
uspto-grants-2013_08
특허 번호
US08518984B2

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