Lithium hydroxide, monohydrate → HCID 57659748, 화합물

HRID 1897556노트

반응식

HRID 1897556 반응식
[C:1]([C:5]1[S:9][C:8]([C:10]([O:12]CC)=[O:11])=[N:7][N:6]=1)([CH3:4])([CH3:3])[CH3:2].O.[OH-].[Li+:17]>C1COCC1.O>[C:1]([C:5]1[S:9][C:8]([C:10]([O-:12])=[O:11])=[N:7][N:6]=1)([CH3:4])([CH3:2])[CH3:3].[Li+:17]

참가 물질

5

반응물 2

HCID 168937Lithium hydroxide, monohydrateHCID 2757341ethyl 5-tert-butyl-1,3,4-thiadiazole-2-carboxylate

생성물 1

HCID 57659748HCID 57659748, 화합물수율 104.1%

시약·촉매·용매 2

HCID 962Water용매HCID 8028Tetrahydrofuran용매

실험 절차

A solution of ethyl 5-tert-butyl-1,3,4-thiadiazole-2-carboxylate (0.21 g, 1.0 mmol) and lithium hydroxide hydrate (42 mg, 1.0 mmol) in THF (2 mL) and water (2 mL) was stirred at room temperature for 18 hours. The solvent was removed under vacuum to give lithium 5-tert-butyl-1,3,4-thiadiazole-2-carboxylate (0.2 g) as a white solid which was used without further purification.

후처리

  1. customThe solvent was removed under vacuum

출처 및 근거

ORD 기록
ord-c18a0196ecd84d47aa546ae2a9eaba82
출처 데이터셋
uspto-grants-2013_08
특허 번호
US08519137B2

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