홈MCP워크벤치Skills
홈워크벤치알림마이페이지
llms.txt · MCP 가이드개인정보처리방침 · 이용약관 · 지원v1.8.0
  1. 홈
  2. /반응

Hydrochloric Acid → 2,3,6,7,8,9-Hexahydro-5-methyl(alpha-methylalanyl)aminomethylfuro-[2,3-f]quinoline-7-one

HRID 1900770
노트
인쇄 미리보기

반응식

HRID 1900770 반응식
Cl.[CH3:2][C:3]1[CH:4]=[C:5]2[CH2:16][CH:15]([CH2:17][NH:18][C:19](=[O:24])[C:20]([CH3:23])([CH3:22])[NH2:21])[O:14][C:6]2=[C:7]2[C:12]=1[NH:11][C:10](=[O:13])[CH:9]=[CH:8]2.[H][H]>O.[Pd]>[CH3:2][C:3]1[CH:4]=[C:5]2[CH2:16][CH:15]([CH2:17][NH:18][C:19](=[O:24])[C:20]([CH3:22])([CH3:23])[NH2:21])[O:14][C:6]2=[C:7]2[C:12]=1[NH:11][C:10](=[O:13])[CH2:9][CH2:8]2
참가 물질실험 절차후처리출처 및 근거반응 노트

참가 물질

6

반응물 3

HCID 313Hydrochloric AcidHCID 233697105-Methyl-2-(alpha-methylalanyl)aminomethyl-2,3,6,7-tetrahydrofuro-[2,3-f]quinoline-7-oneHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 867499952,3,6,7,8,9-Hexahydro-5-methyl(alpha-methylalanyl)aminomethylfuro-[2,3-f]quinoline-7-one수율 82%

시약·촉매·용매 2

HCID 23938Palladium촉매
HCID 962Water용매

실험 절차

A hydrochloric acid salt of 5-methyl-2-(α-methylalanyl)aminomethyl-2,3,6,7-tetrahydrofuro-[2,3-f]quinoline-7-one (1.15 g, 3.27 mmol) was dissolved in water (30 ml). To the obtained solution, 10% palladium-on-carbon (1.15 g) was added, followed by stirring at 80° C. for 3.5 hours in the atmosphere of hydrogen. The reaction mixture was filtered, and the filtrate was condensed under reduced pressure. The resultant residue was subjected to a recrystallization procedure using methanol--ether to obtain 851 mg of the title compound as colorless powdery crystals (73.5%).

후처리

  1. filtrationThe reaction mixture was filtered
  2. customcondensed under reduced pressure
  3. customThe resultant residue was subjected to a recrystallization procedure

출처 및 근거

ORD 기록
ord-1f2c2a88dfc54b5a8bb0084a4b19bf38
출처 데이터셋
uspto-grants-1996_11
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US05576324

반응 노트

불러오는 중…

이 페이지에서참가 물질실험 절차후처리출처 및 근거반응 노트