Ethylenediamine → HCID 19701537, 화합물
반응식
[F:1][C:2]1[CH:11]=[C:10]([N:12]=[C:13]=[S:14])[C:9]([CH3:15])=[C:8]2[C:3]=1[CH:4]=[CH:5][CH:6]=[N:7]2.[CH2:16]([NH2:19])[CH2:17][NH2:18]>C1(C)C=CC=CC=1>[F:1][C:2]1[CH:11]=[C:10]([NH:12][C:13]([NH:18][CH2:17][CH2:16][NH2:19])=[S:14])[C:9]([CH3:15])=[C:8]2[C:3]=1[CH:4]=[CH:5][CH:6]=[N:7]2참가 물질
4
실험 절차
A solution of 5-fluoro-8-methyl-7-quinolinylisothiocyanate (0.38 g) in toluene (40 mL) is added dropwise to a solution of 1,2-ethylenediamine (0.78 g) in toluene (40 mL). A white precipitate is observed after the reaction stirs for 10 minutes at room temperature. The precipitate is filtered and dried in vacuo to afford N-(5-fluoro-8-methyl-7-quinolinyl)-N'-2-aminoethylthiourea as a white solid.
후처리
- filtrationThe precipitate is filtered
- customdried in vacuo
출처 및 근거
- ORD 기록
- ord-953029ded37a4e20b8ea093dbdc459e5
- 출처 데이터셋
- uspto-grants-1996_11
- 특허 번호
- US05576437
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